Poly(p-dioxanone-co-Nε-carbobenzoxy-L-lysine):Synthesis and Mechanism of Copolymerization
WANG Bing1, DONG Jun1, CHEN Dong-liang2, XIONG Cheng-dong2
1. Department of Chemistry, School of Basic Medical Science, North Sichuan Medical University, Nanchong 637000, China; 2. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China
Abstract：The copolymers(PPCLAs), poly(p-dioxanone-co-Nε-carbobenzoxy-L-lysine), were synthesized by bulk copolymerization of p-dioxanone with Nε- carbobenzoxy-L-lysine-N-carboxyanhydride. The structures were characterized by 1H NMR and GPC. The effects of catalyst quantities and reaction time on the average molecular weights of PPCLAs were investigated. The copolymerization mechanism was deduced as “competitive initiate-condensation polymerization between macromolecules”.
2016, Vol. 24 
